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December 03, 2009

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Normally, inflammation is the way the body responds to an injury or to the presence of disease agents, such as viruses or bacteria. During this reaction, many cells of the body's defense system (called the immune system) rush to the injured area to wipe out the cause of the problem, clean up damaged cells and repair tissues that have been hurt. Once the "battle" is won, the inflammation normally goes away and the area becomes healthy again.

In many forms of arthritis, the inflammation does not go away as it should. Instead, it becomes part of the problem, damaging healthy tissues of the body. This may result in more inflammation and more damage - a continuing cycle.

The damage that occurs can change the bones and other tissues of the joints, sometimes affecting their shape and making movement hard and painful. Diseases in which the immune system malfunctions and attacks healthy parts of the body are called autoimmune diseases.

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